SELECTED MAIN-AUTHOR ORIGINAL PUBLICATIONS IN DECILE 1

(to see an updated list of publications follow this link)

 

 

 

 

• SWI/SNF complexes in hematological malignancies: biological implications and therapeutic opportunities.

Authors: Alvaro Andrades*, Paola Peinado *, Juan Carlos Alvarez-Perez* Juan Sanjuan-Hidalgo, Daniel J Garcia, Alberto M Arenas, Ana M Matia-González, Pedro P Medina.

Journal: Molecular Cancer (2023). IF=43, Decile 1

https://doi.org/10.1186/s12943-023-01736-8

 

• Defining the first bona fide cell model for SMARCA4-deficient, undifferentiated tumor.

Authors: Arenas AM, Ruiz-Jiménez JM, López-Hidalgo JL, Sanjuán-Hidalgo J, Medina PP.

Journal: Journal of Pathology (2023). IF=10 Decile 1

https://doi.org/10.1002/path.6141

 

• BCL7A is silenced by hypermethylation to promote acute myeloid leukemia.

Authors: Patiño-Mercau JR, Baliñas-Gavira C, Andrades A, Benitez-Cantos MS, Rot AE, Rodriguez MI, Álvarez-Pérez JC, Cuadros M, Medina PP.

Journal: Biomarker Research (2023). IF=11 Decile 1

https://doi.org/10.1186/s40364-023-00472-x

 

• Recurrent splice site mutations affect key diffuse large B-cell lymphoma genes.

Authors: Andrades A, Peinado P, Alvarez-Perez JC, Sanjuan-Hidalgo J, García DJ, Arenas AM, Matia-González AM, Medina PP.

Journal: Blood (2022). IF=22,5, Decile 1

https://doi.org/10.1182/blood.2021011708

 

• PKP1 and MYC create a feedforward loop linking transcription and translation in squamous cell lung cancer.

Authors: Laura Boyero, Joel Martin-Padron, María Esther Fárez-Vidal, Maria Isabel Rodriguez, Álvaro Andrades, Paola Peinado, Alberto M Arenas, Félix Ritoré-Salazar, Juan Carlos Alvarez-Perez, Marta Cuadros, Medina P.P.

Journal: Cellular Oncology (2022). IF=6,7, Decile 1

https://doi.org/10.1007/s13402-022-00660-1

 

• Recurrent mutations on amino-terminal BCL7A domain promote diffuse large B-cell lymphoma.

Authors: Carlos Baliñas-Gavira, María I. Rodríguez, Alvaro Andrades, Marta Cuadros, Juan Carlos Álvarez-Pérez, Ángel F. Álvarez-Prado, Virginia G. de Yébenes, Sabina Sánchez-Hernández, Elvira Fernández-Vigo, Javier Muñoz, Francisco Martín, Almudena R. Ramiro, José A. Martínez-Climent, Medina PP.

Journal: Leukemia, volume 34, pages 2722–2735 (2020). IF=11,5, Decile 1

https://doi.org/10.1038/s41375-020-0919-5

 

• Plakophilin 1 enhances MYC translation, promoting squamous cell lung cancer

Authors: Joel Martin-Padron, Laura Boyero, Maria Isabel Rodriguez, Alvaro Andrades, Inés Díaz-Cano, Paola Peinado, Carlos Baliñas-Gavira, Juan Carlos Alvarez-Perez, Isabel F. Coira, María Esther Fárez-Vidal, Medina PP.

Journal: Oncogene, volume 39, pages 5479–5493 (2020). IF=10, Decile 1

https://doi.org/10.1038/s41388-019-1129-3

Included in the "The best of Oncogene" issue.

 

 

• Expression of the long non-coding RNA TCL6 is associated with clinical outcome in pediatric B-cell acute lymphoblastic leukemia.

Authors: Cuadros M, Andrades Á, Coira IF, Baliñas C, Rodríguez MI, Álvarez-Pérez JC, Peinado P, Arenas AM, García D, Jiménez P, Camós M, Jiménez-Velasco A, and Medina PP.

Journal: Blood Cancer J. (2019). IF=11, Decile 1

https://doi.org/10.1038/s41408-019-0258-9

Included in the "The best of Blood Cancer Journal" issue.

Article featured in the “article of the month" September 2020 by the SEBBM.

 

 

• Expression inactivation of SMARCA4 by microRNAs in lung tumors.

Authors: Coira IF, Rufino-Palomares EE, Romero OA, Paola Peinado, Chanatip Metheetrairut, Boyero-Corral L, Carretero J, Farez-Vidal E, Cuadros M., Reyes-Zurita F, Lupiáñez JA, Sánchez-Cespedes M., Slack FJ, Medina PP.

Journal: Human Molecular Genetics. 2015 (Decile 1).

https://doi.org/10.1093/hmg/ddu554

Awarded "best publication of 2014-2015" by the Royal Academy of Medicine of Salamanca.

 

• OncomiR addiction in an in vivo model of miR-21-induced pre-B cell lymphoma

Authors: Medina PP, Nolde M and Slack FJ

Journal: Nature. 467, 86-90 2010 8th Aug. (Decile 1).

https://doi.org/10.1038/nature09284

• Ranked at “top 2% of published articles in biology and medicine” by Faculty of 1000 (a post-publication peer review service). http://f1000.com/6381959

The results of this work have been highlighted or commented in the following articles:

• MicroRNAs As Onco-miRs, Drivers of Cancer (PMID: 20739651; Journal of the National Cancer Institute).
• Research Highlights (Nature Reviews Cancer; September 2010, VOL 10 Number 9),
• The Meaning of 21 in the MicroRNA World: Perfection Rather than Destruction (PMID: 20832748, Cancer Cell Volume 18, Issue 3, 203-205).
• miRNA Addiction Depending On Life’s Little Things (PMID: 20869610; Current Biology).
• MicroRNA Gene Added to 'Elite List' of Critical Cancer Genes (BioWorld, August 10th, 2010).

Highly cited article with more than 500 cites in less than 5 years after publication  according Google Scholar.

 

• Regression of murine lung tumors by the let-7 microRNA.

Authors: Trang P* & Medina PP*, Wiggins JF, Ruffino L, Kelnar K, Omotola M, Homer R,  Brown D, Bader AG, Weidhaas JB and Slack FJ

(*) Joint First-author

Journal: Oncogene 2010 (Decile 1).

https://doi.org/10.1038/onc.2009.445

Highly cited article with more than 300 cites in less than 5 years after publication according Google Scholar.

 

• The SRY-HMG box gene, SOX4, is a target of gene amplification at chromosome 6p in lung cancer.

Authors: Medina PP,  Castillo SD, Blanco S, Sanz M, Largo C, Alvarez S, Yokota J, Clevers HC, Cigudosa JC, Lazo PA, Sanchez-Cespedes M.

Journal: Human Molecular Genetics 2009 Apr 1;18(7):1343-52 (Decile 1).

https://doi.org/10.1093/hmg/ddp034

 

• Frequent Brg1/Smarca4-Inactivating Mutations In Human Lung Cancer.

Authors: Medina PP, Romero O, Kohno T, Montuenga LM, Pio R, Yokota J. and Sanchez-Cespedes M.

Journal: Human Mutation 2008 Apr 3;29(5):617-622. (Decile 1).

https://doi.org/10.1002/humu.20730